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Arturo Saavedra, MD, PhD

Dermwiz is a searchable database of non-tumoral skin diseases. It provides a list of diseases that match criteria selected by the user from a vast menu covering clinical and pathological aspects of diseases. Since the database contains descriptions of nearly all diseases and variants, it will yield differential diagnoses containing both common and rare conditions. A simple question validated questionnaire that has been used in over 40 different skin conditions in over 80 countries and is available in over 90 languages. The DLQI is the most frequently used instrument in studies of randomised controlled trials in dermatology.

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Atlas of Dermatology in Internal Medicine

An encyclopedic listing of dermatology disorders sorted by type, with descriptions of etiology, symptoms, diagnosis, prognosis, and treatment. Rich results from a dermatology search in the database simultaneously show results from PubMed, PubMed Central, online books, Nucleotide sequence database, Protein sequence database, and much more. Occupational Skin Infections. A quick table of a list of occupations, the high-risk job task involved, and the potential diseases and infections that can result. This is a database of most of the published articles and books on dermatology, run by the National Library of Medicine and the National Institutes of Health.

There are currently more than 17, dermatology focused and dermatology related publications listed, with title, author, and abstracts available, with articles linked to others of related interest. If full text is available online PubMed will link to it. The Internet Drug Index enables advanced searching by keyword, side effect, interaction, name, pill id, imprint codes, NDC codes, and medical terminology, as well as maintaining a list of the top most recent drug name searches and the top prescriptions for by number of U.

A clinical tool for assessing the severity of atopic dermatitis as objectively as possible. Skinsight Skin Condition Finder. This online tool allows you to identify skin conditions in three easy steps - choose your age, the location of the condition, and then view photographic matches to determine your skin condition. Matches have several pages of additional information, including overview, who's at risk, symptoms, self-care, and treatments. Cutaneous manifestations of TB are very rare and only represent 1.

Several published studies have revealed that cutaneous TB is best diagnosed using a com- Endogenously Acquired Disease prehensive work up of the patient in which histologic study of the skin biopsy specimen is most essential [61]. Skin Lupus Vulgaris lesions are distinguished by whether M. Up to merase chain reaction PCR.

Its pathogenesis is mul- cutaneous tuberculosis.

Atlas of dermatology in internal medicine (decenber edition)

True cutaneous tuberculosis can be tifactorial: direct inoculation, BCG vaccination, contiguous, acquired exogenously or endogenously and includes such lymphatic, and hematogenous route of infection [49, 65]. The lesions may present in a variety of morphologies from an infected lymph node, bone, joint, or epididymis to including the classic plaque or keratotic type gelatinous , the overlying skin in patients with a weak immune response the hypertrophic form tumor-like soft nodule , the ulcerative [69, 72, 73].

This is the most common cutaneous TB in chil- form necrosis , and the vegetative form papule with ulcer- dren and it is more common in girls than in boys [42, 57, 66, ation and necrosis. The plaque form is the most common 69]. It initially unpasteurized milk is a common occurrence around the presents as asymptomatic, flat, red-brown papules and world that leads to the M.

It progresses into slowly expanding skin-colored or lymph nodes [49, 66, 69, 72, 73].


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On diascopy, the nodules are seen as nodule overlying the site of the deeper infection. Over a period of color. The expanding plaque has an atrophic center with a months, it begins to ulcerate, eventually forming the hall- raised red-brown border, occasionally with scaling [67]. The mark sinus tracts that drain watery, purulent, or caseous ulcerative form is the most destructive and deforming of all material [49, 60, 72].

The ulcers are shallow with undermined LV lesions because the underlying tissue becomes ulcerated blue-colored borders. Healing forms an elongated scar or and necrotic, leaving behind an atrophic scar. It can be espe- keloid, the characteristic puckered scar [49, 59, 60]. Finally, the vegetative form is similar to the ulcer- infection, especially pulmonary involvement [49, 59, 66, ative form in that it is characterized by necrosis and ulcer- 69]. The most commonly affected 59]. After many decades with the disease, squamous cell car- area is the neck, but may also occur on the axillae, chest, or cinoma may develop in the lupus vulgaris lesion [67, 68].

At times, lupus vulgaris may arise The areas in the body where these lesions appear vary from scrofuloderma. This form of cutaneous TB may take among different places in the world. In Western countries, LV several years to spontaneously heal [49, 59, 71].

It is also referred to as [69]. In the tropics and developing countries, on the other metastatic tuberculous abscesses that arise on the trunk, hand, where kids play without protective clothing, it occurs extremities, or head [46, 47, 49, 54, 59, 74]. It occurs after most often on the lower extremities and buttocks [42, 49].

It occurs in patients with moderate to high immunity against M. Since Acute miliary tuberculosis is the extensive dissemination of lupus vulgaris is a paucibacillary form of tuberculous infec- M.

The internal focus based on the histopathological appearance and the response of the active disease most commonly originates from the lungs. This rare form of TB has become increasingly common among The histopathologic examination shows the hallmark tuber- HIV-infected patients. The first documented case that presented cles, which consist of accumulations of epithelioid histiocytes with cutaneous findings was reported in in an AIDS with Langerhans giant cells and varying amount of caseation patient [75]. Patients with acute miliary TB usually have a seri- necrosis in the center [71].

As a result, they have a with intermittent episodes of healing. Neither caseation necro- poor prognosis, with many cases leading to death [49, 59].


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  • It is the additional clinical criteria that is pura, and uncommonly, umbilicated vesicles [49, 60, 71—73]. By the fourth week, the lesions are the apple-jelly nodules revealed by diascopy [71]. Histology confirms Scrofuloderma the diagnosis, revealing multiple microabscesses with neu- Scrofuloderma, also known as tuberculosis cutis colliqua- trophils and numerous AFB organisms surrounded by mac- tiva, arises from the extension of underlying tubercle bacilli rophages and giant cells [49, 60]. Recognizing this cutaneous sore may persist, on the upper outer arm, which imitates the lesion is significant because it indicates advanced internal TB chancre, but is referred to as a BCG granuloma.

    It tends disease and poor prognosis. It presents as red- or yellow- to occur 2—6 weeks after vaccination. It appears as a small colored nodules that ulcerate around the mucosal orifices, solitary brown nodule or papule that ulcerates, scabs, and such as on the lips, inside the mouth, or on the anogenital heals as a scar [62, 72]. These painful ulcers have an irregular circular shape, with an undermined border and a shallow, punched-out, and Tuberculosis Verrucosa Cutis granulomatous appearance.

    It spreads to infect the mucosa or TVC results from a reinfection with M. Since this cutaneous mani- anus orifice [49, 59, 60, 74]. Perianal tuberculosis is believed festation entails reinfection, it occurs most often in those to be a consequence of auto-inoculation from swallowed who have occupational exposure, such as physicians bacilli-containing sputum through defects in the perianal especially pathologists or forensic scientists , other medical mucosa [71].

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    This cutaneous variant of TB occurs in patients with strong cell-mediated immunity. The lesion first appears as a small, solitary, asymptomatic, Exogenously Acquired Disease and reddish-brown papule that progresses into a large, irreg- ular verrucous plaque [49, 60]. The margins are firm while Tuberculous Chancre the center is soft, and there is a surrounding erythematous The tuberculous chancre, also known as the primary inocula- border.


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    • There are deep fissures on the surface which often tion tuberculosis, is seen following primary infection with expel pus [49, 59]. TVC is found most commonly on the M. There have been cases test [49, 59, 60].

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      They 47, 49, 54, 59]. The tubercle bacilli cannot penetrate intact persist for several years slow growing and chronic in nature , skin, thus only after the patient suffers some sort of skin but they eventually heal spontaneously with an atrophic scar trauma or minor abrasion can the organism infiltrate and [49, 77]. It has also been reported to occur post- Histology reveals hyperkeratosis and papillomatosis of mouth-to-mouth resuscitation, jail-house tattooing, circum- the epidermis.